科学研究:承担“药用辅料关键质量属性的评价技术与功能性指标数据库的建立““抗流感病毒类Nucleozin衍生物的设计、合成和生物活性评价”等自然科学基金项目5项;承担“不同产地青蒿的质量评价”等横向科研项目1项;发表高水平学术论文11篇。
教研教改:承担《生物化学实验》《仪器分析实验》《药物分析实验》等本科课程教学;参与省部级教研教改项目2项,指导大学生创新创业项目1项。
代表性学术成果:
1.期刊论文
[1] Guo X. , Guan T. , Qiang L I , et al. Applications of Metabonomics Integrated with Bioinformatics Strategy in Analyzing the Systems Complexity of Traditional Chinese Medicines[J]. Progress in Pharmaceutical Sciences, 2014.
[2] Su, Q.;Xu, G.; Guan, T. B.; Que, Y.; Lv, H.T.*;Mass spectrometry-derived systems biology technologies delineate the system's biochemical applications of siderophores,Mass Spectrometry Reviews, 2016,1-14.
[3] Su, Q.; Guan, T. B.; He, Y.; Lv, H.T.*;Siderophore biosynthesis governs the virulence of uropathogenic Escherichia coli by coordinately modulating the differential metabolism, Journal of Proteome Research, 2016, 15(4): 1323-1332.
[4] Su, Q.; Guan, T. B.; Lv, H.T.*;Siderophore biosynthesis coordinately modulated the virulence-associated interactive metabolome of uropathogenic Escherichia coli and human urine, Scientific Reports, 2016, 6:24099-24109.
[5] Haitao, Yumei, Que, Tianbing, Guan, et al. Metabolomics Deciphered Metabolic Reprogramming Required for Biofilm Formation.[J]. Scientific reports, 2019, 9(1):13160-13160.
[6] Shulin Wan, Chuanyun Dai,* Yuling Bai, Wenying Xie, Tianbing Guan, Huimin Sun,* and Bochu Wang*,Application of Multivariate Methods to Evaluate Differential Material Attributes of HPMC from Different Sources.[J].ACS Omega 2021, 6, 28598−28610
[7] Li Y, Long H, Jiang G, Gong X, Yu Z, Huang M, Guan T, Guan Y, Liu X. Analysis of the ethanol stress response mechanism in Wickerhamomyces anomalus based on transcriptomics and metabolomics approaches.[J].BMC Microbiol. 2022, 22(1):275.
2.科研项目
1.重庆自然科学基金委员会,面上项目,CSTC2019JCYJ-MSXMX0083,抗流感病毒类Nucleozin衍生物的设计、合成和生物活性评价, 2019-07至2022-06,5万
2.重庆市璧山国家农业园区管委会,优质果蔬快繁及精深加工技术中心建设,2020-05至2021-05,20万
3.国家科技部,重大专项,“药物一致性评价关键技术与标准研究”子课题六“药用辅料关键质量属性的评价技术与功能性指标数据库的建立”, 2018-01至2020-12,2万
4.重庆市璧山国家农业园区管委会,特色植物良种组培快繁技术开发及推广应用,2016-10至2019-10,120万
5.重庆市中药研究院,不同产地青蒿的质量评价,2016-12至2017-12,5万