承担“手性亚砜-膦杂化配体设计及铜/铑催化不对称共轭加成反应“ “脂多糖生物合成抑制剂的设计合成和抗菌活性研究““喜树碱C11位新衍生物的合成及构效关系研究“等自然科学基金项目3项，承担“乙肝类抗病毒药物中间体的合成技术开发”横向科研项目1项，在J. Am. Chem. Soc., Chinese J. Catal. , Spectrochimica Acta Part A. 等重要国际学术刊物上发表系列学术论文20余篇，授权发明专利1项。承担《无机化学》、《有机合成化学》等本科生课程教学，承担校级教改项目1项，发表教改论文2篇，指导研究生10名，指导大学生创新创业项目3项。
代表性学术成果：
1. J. Chen, Q. Zhou, W. Hu, Y.-X. Yao, L.-L .Cheng, F.-T. Yang, C.-Y. Sun, S. Guan, S.-C. Pei Preparation of new small-molecule fluorescent probes and their application in fluoride ion detection. Dyes and Pigments 2026, 253: 113875
2. J. Chen, Y.-X. Yao, X.-Y. Pei, M.-T. Qu, J.-H. Zhang, W.-Hu, Y.-Y. Zhang, W. Wu, S.-C. Pei. A multifunctional near-infrared fluorescent probe based on benzothiazole structure for fluoride-ion detection, 2025, 324: 125009
3. J. Chen, M.-T. Qu, J.-H. Zhang, Y.-X. Yao, X.-Y. Pei, Wen Wu, S.-C. Pei A novel fluorescent probe for efficient detection of fluoride ions in living animal and plant tissues . Anal. Methods, 2024, 16: 7139-7147
4. S.-C. Pei, C.-Z. Li, X.-Y. Pei, X.-L. Liao, J. Chen* Dual colorimetric and near-infrared fluorescence probe for Hg2+ detection and cell imaging Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy , 2023, 285: 121886
5. J. Chen, F. Lang, J. Liao. A C2-Symmetric Chiral Bis-Sulfoxide Ligand in a Rhodium-Catalyzed Reaction: Asymmetric 1,4-Addition of Sodium Tetraarylborates to Chromenones J. Am. Chem. Soc. 2010, 41(33) : 4552-4553.
6. J. Chen, F. Xue, H.-Y. Fu, H. Chen, X.-J. Li Chinese J. Catal., 2007, 28(11): 975-979
